We wish each and every one of The WELL’s readers a Happy New Year.  In the coming year, we aspire for a world that experiences significantly greater freedom, joy, and health.  Despite our optimism, we predict that 2022 will be a turbulent year for those affected by the Toxic Substances Control Act (TSCA).  One has to look no further than EPA’s Regulatory Agenda to expect a substantial amount of action from the Agency this year.  As the last year has taught everyone, TSCA is no longer only a chemical manufacturers’ law.  Indeed, the coming wave of TSCA regulations will significantly impact downstream users (e.g., manufacturers and importers of articles and mixtures).